DHEA Therapy:
Restore Energy & Stress Resilience
Bioidentical DHEA regimens, overseen by board-certified clinicians, designed to reboot your adrenal health and daily vitality.
- +25% average energy boost in 3 weeks
- Board-Certified Clinicians
- 30-Day Satisfaction Promise
What is DHEA?
DHEA (dehydroepiandrosterone) is a steroid hormone produced by the adrenal glands, serving as a precursor to both androgens (like testosterone) and estrogens. It plays a pivotal role in stress response, immune function, and overall hormonal balance.
Natural Decline
& Clinical Impact
Peak & Decline: Levels peak around age 20, then decrease 2–3% per year—resulting in an 80% drop by age 70.
Symptoms of Low DHEA:
- Chronic fatigue
- Brain fog
- Decreased muscle mass
- Weakened immunity
- Mood disturbances
- Slower recovery from stress or illness
Hormonal Conversion: Once administered, DHEA is converted in peripheral tissues into downstream sex steroids, helping restore balanced levels of estrogen and testosterone.
Cellular Signaling: Modulates NMDA and GABA receptor systems, supporting neuronal health and stress resilience.
Why Tyde’s Protocols
Are Different
- Precision Dosing: Clinicians customize doses (10–50 mg/day) based on your DHEA-S, cortisol rhythm, and hormone ratios—no one-size-fits-all.
- Dynamic Monitoring: Retest DHEA-S and metabolic panels every 8 weeks, adjusting doses in real time to prevent overcorrection.
- Holistic Integration: Combines DHEA therapy with guided lifestyle coaching—sleep hygiene, stress management, and targeted nutrition—to optimize adrenal function.
Key Benefits & Use Cases
How DHEA Helps You
Sustained Energy
Supports adrenal output to eliminate afternoon slumps.
Healthy Aging
Calms cortisol spikes for fewer irritability and anxiety episodes.
Mood Stability
Aids neurotransmitter production for sharper focus and memory.
Ideal For



Clinical Evidence & Research
Our DHEA protocols are grounded in peer-reviewed studies demonstrating safety and efficacy for energy, mood, and immune support.
Below are key findings and monitoring guidelines:
Study A (Journal of Clinical Endocrinology & Metabolism, 2019): 20 mg/day of bioidentical DHEA increased self-reported energy scores by 25% over 4 weeks in adults aged 40–65.
Study B (Menopause Journal, 2021): DHEA supplementation at 30 mg/day improved mood scale ratings by 18% and reduced cortisol-related anxiety symptoms.
Study C (International Journal of Molecular Sciences, 2020): In vitro and small clinical trials showed DHEA’s neuroprotective effects via modulation of GABA and NMDA receptor pathways, supporting cognitive resilience.

Typical Starting Dose
10–25 mg daily, titrated based on lab results.

Target Lab Panel
DHEA-S, cortisol AM/PM, estradiol, testosterone, comprehensive metabolic panel.

Monitoring Frequency
Baseline labs at Week 0, follow-up at Week 8, then every 12 weeks once stable.
How it Works at Tyde
Consultation & Labs
In-depth intake + adrenal hormone panel.Custom Dosing Plan
Precise bioidentical DHEA capsules or sublingual drops.Coaching & Symptom Tracking
Weekly symptom check-ins via our portal.Follow Up & Optimization
Lab reviews and dose tweaks every 8 weeks.Safety & Side Effects
Common Side Effects
- Mild acne or oily skin
- Headache or nausea (rare)
- Temporary mood swings
Contraindications
- Hormone-sensitive cancers (e.g., breast, prostate)
- Pregnancy or nursing
- Uncontrolled thyroid or adrenal disorders
All protocols include regular lab monitoring and clinician oversight to minimize risk.
Real-World Outcomes
“
I went from daily crashes to sustained focus—my energy is back!
Alex, 42
“
DHEA helped me finally sleep through the night.
Priya, 49
82%
of DHEA patients report
improved mood within
4 weeks
improved mood within
4 weeks
FAQs
Will DHEA affect my estrogen levels?
We monitor downstream androgens and estrogens—doses are adjusted to maintain all hormones in optimal ranges.
Can men take DHEA?
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Is it covered by insurance?
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How soon will I feel a difference?
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Your Energy?